Giraldo can usually be seen performing stand up comedy at the Comedy Cellar in Manhattan. In his career he starred in several pilots, including The Greg Giraldo Show and Gone Hollywood for Comedy Central. The comic also appeared in several shows like 'The late Show with David Letterman", "The Howard Stern Show" and was a panelist on Comedy Central's 100 Greatest Stand-ups of All Time. On comedy Central presents Greg Giraldo had two half-hour specials.
The comedian also appeared in Comedy Central's annual comedy roasts getting the chance to roast Chevy Chase, Pamella Anderson, William Shatner, Jeff Foxworthy, Flavor Flav, Bob Saget and Larry The Cable Guy.
In the year 2006 Greg Giraldo released his humorous CD "Good Day to Cross a River" on Comedy Central Records.
